Cardiovascular Clinical Trials
The Methodist Hospitals Heart and Vascular Institute is dedicated to delivering the best cardiovascular are in Northwest Indiana. That commitment extends to participating in these clinical trials and research focused on developing new treatments for heart and vascular conditions.
The Lipid-Rich Plaque Study (LRP).
Many studies in patients who have already experienced a coronary problem point to the danger associated with plaques that are rich in cholesterol. This study determines if the near-infrared method of detection of these fatty plaques can predict future events. If dangerous plaques can be identified, there are many treatments already available that could be tested for their ability to prevent coronary events
PLATINUM Diversity: Outcomes With the Premus PREMIER™ Stent in Women and Minorities
Sponsor: Boston Scientific
This study compiles acute procedural performance and clinical outcomes data for the Promus PREMIER everolimus-eluting coronary stent system in understudied/underserved patient populations including women and minorities.
Best Endovascular vs. Best Surgical Therapy in Patients with Critical Limb Ischemia (BEST CLI)
Sponsor: New England Research Institutes
This study compares the effectiveness of best available surgical treatment with best available endovascular treatment in adults with critical limb ischemia (CLI) who are eligible for both treatment options
A Study to Assess the Effectiveness and Safety of Rivaroxaban in Reducing the Risk of Death, Myocardial Infarction or Stroke in Participants With Heart Failure and Coronary Artery Disease Following an Episode of Decompensated Heart Failure (COMMANDER HF)
Sponsor: Janssen Research & Development, LLC
The purpose of this study is to assess the effectiveness and safety of rivaroxaban compared with placebo (inactive medication), in reducing the risk of death, myocardial infarction or stroke in participants with heart failure and significant coronary artery disease following an episode of decompensated heart failure.
Examining the Use of Ticagrelor In Peripheral Artery Disease (EUCLID)
The purpose of this study is to compare the effects of ticagrelor and clopidogrel in patients with Peripheral Artery Disease.
Cardiovascular Inflammation Reduction Trial (CIRT)
Sponsor: Brigham and Women’s Hospital. Collaborator: National Heart, Lung and Blood Institute (NHLBI)
The Cardiovascular Inflammation Reduction Trial (CIRT) is a randomized clinical trial investigating whether taking low-dose methotrexate reduces heart attacks, strokes, or death in people with type 2 diabetes or metabolic syndrome that have had a heart attack or multiple coronary blockages.
AngelMed for Early Recognition and Treatment of STEMI (ALERT)
Sponsor: Angel Medical Systems
This is a prospective, randomized multicenter study of subjects with a high-risk of having a myocardial infarction (MI) due to acute coronary syndrome or bypass surgery.
Please contact Kim Armstrong, RN, Clinical Research Coordinator, at the Heart Centers at 219-884-9180 or by email at firstname.lastname@example.org.
CLICK HERE to meet the Methodist Physician Group cardiology specialists practicing near you.
Methodist Hospitals Heart and Vascular Institute
Northlake Campus: 600 Grant Street, Gary, IN 46402
Southlake Campus: 8701 Broadway, Merrillville, IN 46410 • 219-738-3472